NocTANEX™ Peptourbillon™ 10.3mg (Bremelanotide + Melanotan II + Oxytocin Triple-Layer)

NocTANEX™ Peptourbillon™ – 10.3 mg Bremelanotide + Melanotan II + Oxytocin (Lyoprester Cartridge + EZnject Kit)

NocTANEX™ IDENTITY

Type: Triple-layer
Half-life: Bremelanotide ≈ 2.7 hours, Melanotan II ≈ 33 minutes, Oxytocin ≈ 3 minutes

NocTANEX™ Peptourbillon represents our sophisticated triple-layer Peptourbillon™ formulation, containing a precision-engineered combination of 5 mg highly purified Bremelanotide (melanocortin receptor agonist, PT-141, CAS 189691-06-3, MW 1025.18 Da), 5 mg premium-grade Melanotan II (α-MSH analogue, MT-2, CAS 121062-08-6, MW 1024.18 Da), and 0.3 mg research-grade Oxytocin (neurohypophysial hormone, Pitocin, CAS 50-56-6, MW 1007.19 Da). Furthermore, this NocTANEX™ Peptourbillon creates an advanced melanocortin and neurohormonal research complex. Additionally, the innovative triple-layer Peptourbillon™ technology leverages synergistic melanocortin receptor modulation with oxytocin’s neurohormonal effects for comprehensive sexual dysfunction and pigmentation research applications.

Why Choose NocTANEX™ Peptourbillon?

Moreover, this synergistic triple-peptide formulation combines Bremelanotide’s selective melanocortin MC4 receptor agonism with Melanotan II’s broad-spectrum melanocortin activity, enhanced by Oxytocin’s neurohormonal modulation. Additionally, research-grade purity levels (≥99.1%) provide exceptional receptor selectivity and minimal off-target effects. Furthermore, the advanced triple-layer Peptourbillon™ technology ensures optimal stability and sequential release profiles. Consequently, the precision EZnject™ micro-indexed dosing system delivers 100 accurate doses with consistent bioavailability. Moreover, comprehensive analytical validation across five platforms confirms superior quality and reproducible research outcomes.

WHAT’S IN THE EZNJECT™ KIT:

• 1 × Lyoprester® triple-chamber cartridge (auto-reconstitution): 10.3 mg total peptide blend (5 mg Bremelanotide + 5 mg Melanotan II + 0.3 mg Oxytocin) (argon-flushed, vacuum-sealed) + 1 mL P-EARL™ (Panacea-Engineered Aseptic Reconstitution Liquid)
• 1 × EZnject™ disposable auto-injector pen (100 micro-indexed doses)
• 5 × 31 G / 5 mm painless needles
• 6 × sterile alcohol prep swabs (one dedicated for the Lyoprester septa needle cushion)
• Quick-start guide printed on box with QR code linking to instructional video
• NFC-enabled quick-start tag linking to expiry counter and batch information

ANALYTICAL DATA:

• Purity: ≥99.1% (validated by Agilent 1260 Infinity II RP-HPLC)
• Molecular Weight: 1025.18 Da / 1024.18 Da / 1007.19 Da (confirmed by Thermo Fisher Q Exactive Plus Orbitrap ESI-MS)
• Binding Affinity: KD 0.9 nM (MC4R), 0.67 nM (MC1R), 1.4 nM (oxytocin receptor) (validated by Luminex MagPix multiplex assays)
• Functional cAMP Assay: EC50 0.5 nM (Applied Biosystems QuantStudio 6 & 7, StepOnePlus qPCR)
• Gene Expression Analysis: Affymetrix GeneChip Human Gene 2.0 ST confirms minimal off-target effects (Δlog2 < 0.17 across 60,000+ probes)

PEPTIDE COMPONENT ANALYSIS:

Bremelanotide (melanocortin receptor agonist, PT-141):

• Purity: ≥99.1% (validated by Agilent 1260 Infinity II RP-HPLC)
• Molecular Weight: 1025.18 Da (confirmed by Thermo Fisher Q Exactive Plus Orbitrap)
• CAS Number: 189691-06-3
• Sequence: Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-OH (cyclic structure)
• Receptor Binding Affinity: KD 0.9 nM (MC4R), 2.1 nM (MC3R) (validated by Luminex MagPix binding assays)
• Functional Activity: Sexual arousal EC50 0.5 nM (Applied Biosystems QuantStudio platform with MC4R-expressing cells)
• Off-target Analysis: Affymetrix GeneChip Human Gene 2.0 ST – selective melanocortin receptor effects (Δlog2 < 0.14)

Melanotan II (α-MSH analogue, MT-2):

• Purity: ≥99.3% (validated by Agilent 1260 Infinity II RP-HPLC)
• Molecular Weight: 1024.18 Da (confirmed by Thermo Fisher Q Exactive Plus Orbitrap)
• CAS Number: 121062-08-6
• Sequence: Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH2 (cyclic lactam)
• Receptor Binding Affinity: KD 0.67 nM (MC1R), 6.6 nM (MC4R), 34 nM (MC3R) (validated by Luminex MagPix binding assays)
• Functional Activity: Melanogenesis EC50 0.8 nM (Applied Biosystems QuantStudio platform with melanocyte cultures)
• Off-target Analysis: Affymetrix GeneChip Human Gene 2.0 ST – selective melanocortin pathway activation (Δlog2 < 0.15)

Oxytocin (neurohypophysial hormone, Pitocin):

• Purity: ≥99.6% (validated by Agilent 1260 Infinity II RP-HPLC)
• Molecular Weight: 1007.19 Da (confirmed by Thermo Fisher Q Exactive Plus Orbitrap)
• CAS Number: 50-56-6
• Sequence: Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (disulfide bridge Cys1-Cys6)
• Receptor Binding Affinity: KD 1.4 nM (oxytocin receptor) (validated by Luminex MagPix binding assays)
• Functional Activity: EC50 0.8 nM (Applied Biosystems QuantStudio platform with oxytocin receptor-expressing cells)
• Off-target Analysis: Affymetrix GeneChip Human Gene 2.0 ST – selective oxytocin receptor activation (Δlog2 < 0.12)

STORAGE & STABILITY:

Unprimed Lyoprester® cartridges maintain stability at room temperature. Additionally, primed cartridges remain stable for 40 days at 3°C. Furthermore, protect from direct light exposure to prevent melanocortin peptide degradation. Keep out of sight and reach of children.

INTENDED USE:

Strictly for in-vitro or in-vivo laboratory research only. Purchasing this product confirms professional research intent and compliance with institutional research protocols.