ExADIPO³™ Peptourbillon™ 12.2mg (Retatrutide + Oxytocin Dual-Layer)

ExADIPO³™ Peptourbillon™ – 12.2 mg Retatrutide + Oxytocin (Lyoprester Cartridge + EZnject Kit)

ExADIPO³™ IDENTITY

Type: Dual-layer
Half-life: Retatrutide ≈ 144 hours, Oxytocin ≈ 3 minutes

ExADIPO³™ Peptourbillon represents our cutting-edge dual-layer Peptourbillon™ formulation, containing a precision-engineered combination of 12 mg highly purified Retatrutide (triple GLP-1/GIP/GCGR receptor agonist, LY3437943, CAS 2381089-83-2, MW 4731.33 Da) and 0.2 mg premium-grade Oxytocin (neurohypophysial hormone, CAS 50-56-6, MW 1007.19 Da). Furthermore, this ExADIPO³™ Peptourbillon creates an advanced metabolic and neuroendocrine research complex. Additionally, the innovative dual-layer Peptourbillon™ technology leverages synergistic triple incretin receptor agonism with oxytocin’s neurohormonal effects for comprehensive physiological research applications.

Why Choose ExADIPO³™ Peptourbillon?

Moreover, this synergistic dual-peptide formulation combines Retatrutide’s unprecedented triple receptor agonism (GLP-1R/GIPR/GCGR) with Oxytocin’s potent neurohypophysial activity. Additionally, research-grade purity levels (≥99.2%) provide exceptional receptor selectivity across multiple incretin pathways. Furthermore, the advanced dual-layer Peptourbillon™ technology ensures optimal stability and controlled release kinetics. Consequently, the precision EZnject™ micro-indexed dosing system delivers 100 accurate doses with consistent bioavailability. Moreover, comprehensive analytical validation across five platforms confirms superior quality and reproducible research outcomes.

WHAT’S IN THE EZNJECT™ KIT:

• 1 × Lyoprester® dual-chamber cartridge (auto-reconstitution): 12.2 mg total peptide blend (12 mg Retatrutide + 0.2 mg Oxytocin) (argon-flushed, vacuum-sealed) + 1 mL P-EARL™ (Panacea-Engineered Aseptic Reconstitution Liquid)
• 1 × EZnject™ disposable auto-injector pen (100 micro-indexed doses)
• 4 × 31 G / 5 mm painless needles
• 5 × sterile alcohol prep swabs (one dedicated for the Lyoprester septa needle cushion)
• Quick-start guide printed on box with QR code linking to instructional video
• NFC-enabled quick-start tag linking to expiry counter and batch information

ANALYTICAL DATA:

• Purity: ≥99.2% (validated by Agilent 1260 Infinity II RP-HPLC)
• Molecular Weight: 4731.33 Da / 1007.19 Da (confirmed by Thermo Fisher Q Exactive Plus Orbitrap ESI-MS)
• Binding Affinity: KD 0.64 nM (GLP-1R), 0.78 nM (GIPR), 5.8 nM (GCGR) (validated by Luminex MagPix multiplex assays)
• Functional cAMP Assay: EC50 0.32 nM (Applied Biosystems QuantStudio 6 & 7, StepOnePlus qPCR)
• Gene Expression Analysis: Affymetrix GeneChip Human Gene 2.0 ST confirms minimal off-target effects (Δlog2 < 0.18 across 60,000+ probes)

PEPTIDE COMPONENT ANALYSIS:

Retatrutide (triple GLP-1/GIP/GCGR receptor agonist, LY3437943):

• Purity: ≥99.2% (validated by Agilent 1260 Infinity II RP-HPLC)
• Molecular Weight: 4731.33 Da (confirmed by Thermo Fisher Q Exactive Plus Orbitrap)
• CAS Number: 2381089-83-2
• Sequence: Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-α-Me-Leu-Leu-Asp-Lys(C20 diacid)-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
• Receptor Binding Affinity: KD 0.64 nM (GLP-1R), 0.78 nM (GIPR), 5.8 nM (GCGR) (validated by Luminex MagPix multiplex binding assays)
• Functional Activity: EC50 0.32 nM (Applied Biosystems QuantStudio platform with HEK293T cells)
• Off-target Analysis: Affymetrix GeneChip Human Gene 2.0 ST – selective incretin receptor effects (Δlog2 < 0.15)

Oxytocin (neurohypophysial hormone, Pitocin):

• Purity: ≥99.6% (validated by Agilent 1260 Infinity II RP-HPLC)
• Molecular Weight: 1007.19 Da (confirmed by Thermo Fisher Q Exactive Plus Orbitrap)
• CAS Number: 50-56-6
• Sequence: Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (disulfide bridge Cys1-Cys6)
• Receptor Binding Affinity: KD 1.4 nM (oxytocin receptor) (validated by Luminex MagPix binding assays)
• Functional Activity: EC50 0.8 nM (Applied Biosystems QuantStudio platform with oxytocin receptor-expressing cells)
• Off-target Analysis: Affymetrix GeneChip Human Gene 2.0 ST – selective oxytocin receptor activation (Δlog2 < 0.12)

STORAGE & STABILITY:

Unprimed Lyoprester® cartridges maintain stability at room temperature. Additionally, primed cartridges remain stable for 40 days at 3°C. Furthermore, protect from direct light exposure. Keep out of sight and reach of children.

INTENDED USE:

Strictly for in-vitro or in-vivo laboratory research only. Purchasing this product confirms professional research intent and compliance with institutional research protocols.